Translation

Welcome to Yuzaki Lab
  • Yuzuzaki Laboratory is a research center for human biology - Microbiota - Quantum Computational Research (Keio University)WPI-Bio2Q) has been moved to
  • Focusing on synaptic formation mechanisms in the central nervous system, peripheral nervous system, autonomic nervous system, and enteric nervous system、We aim to clarify the linkage between the nervous system and multiple organs, and the pathology caused by its failure, and to develop treatment methods.
Past News
Journal Club
Recruiting!
We await the participation of motivated indivisuals。We will vigorously nurture young researchers who will lead the future of basic science.。
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   Contact usClick here.

2009


Voltage-gated sodium channel gene refractory epilepsy patients (αII gene SCN2A) novel mutation was found in (Neurology) 2009.12.31
Ogiwara I., Ito K., Sawaishi Y., Osaka H., Mazak E., Inoue I., Montal M., Hashikawa T., Shike T., Fujiwara T., Y. Inoue, Kaneda M., Yamakawa K. De novo mutations of voltage-gated sodium channel alphaII gene SCN2A in intractable epilepsies. Neurology,73:1046-1053, 2009.


Efficient way of differentiating Purkinje cells from mouse ES cells (J Neurosci Res) 2009.9.2
The Tao, Shimazaki T, Okada Y, Naka H, Kohda K, Yuzaki M, Mizusawa H, Okano H. Efficient generation of mature cerebellar Purkinje cells from mouse embryonic stem cells. J Neurosci Res 88:234-47,2010.
http://www3.interscience.wiley.com/journal/122574713/abstract


AP-AMPA receptors are transported to dendrites by four polar (invited review; Neurosci Res) 2009.5.29
Matsuda, S., Yuzak, M. Polarized Sorting of AMPA Receptors to the Somatodendritic Domain Is Regulated by Adaptor Protein AP-4. Neurosci. Res., 65:1-5, 2009
http://www.ncbi.nlm.nih.gov/pubmed/19481121


most N-terminal region of δ2 receptors are rapidly induced in the cerebellar parallel fiber synapses in vivo (J Neurosci) 2009.3.26
Kakegawa, W., Miyazaki, T., Kohda, K., Matsuda, K., Emi, K., Motohashi, J., Watanabe, M., Yuzaki, M. The N-terminal domain of GluD2 (GluRd2) recruits presynaptic terminals and regulates synaptogenesis in the cerebellum in vivo, J. Neurosci. 29:5738-5748, 2009
http://www.jneurosci.org/cgi/content/abstract/29/18/5738


Cbln1 expressed by neuronal activity is suppressed - in the homeostatic control during development and maturation (J Neurosci) 2009.3.24
Iijima, T., Emi., K., Yuzaki, M. Activity-dependent repression of Cbln1 expression: mechanism for developmental and homeostatic regulation of synapses in the cerebellum. J. Neurosci.29:5425-5434、2009.
http://www.jneurosci.org/cgi/content/abstract/29/17/5425


Glutamate receptor delta-receptors and NMDA receptor (Invited review; Handbook of Neurochem & Mol Neurobiol) 2009.1.8
Yuzaki, M. Glutamate Receptors: NMDA and Delta Receptors. In: Neural Signaling Mechanisms (Mikoshiba, C. and), Handbook of Neurochemistry and Molecular Neurobiology (Lajtha, A. ed-in-chief), , Springer, New York, 2009, in press.
http://www.springer.com/biomed/neuroscience/book/978-0-387-30338-3


Endogenous Cbln1 parallel fiber - Cbln3 and δ2 receptor is localized with Purkinje cells in the synaptic cleft (Eur J Neurosci) 2009.1.1
Miura, E., Matsuda, K., Morgan, J.I., Yuzaki, M., Watanabe, M. Cbln1 accumulates and colocalizes with Cbln3 and GluRδ2 at parallel fiber-Purkinje cell synapses in the mouse cerebellum. Eur. J. Neurosci. 29:693–706, 2009.
http://www3.interscience.wiley.com/journal/122205921/abstract


Recombinant Cbln1 specifically bind to the postsynaptic parallel fiber Purkinje cell synapses over (Eur J Neurosci) 2009.1.1
Matsuda, K., Kondo, T., Iijima, T., Matsuda, S., Watanabe, M., Yuzaki, M. Cbln1 binds to specific postsynaptic sites at parallel fiber–Purkinje cell synapses in the cerebellum. Eur. J. Neurosci. 29:707-717, 2009.
http://www3.interscience.wiley.com/journal/121683096/abstract?CRETRY=1&SRETRY=0