Keiko Matsuda lecturer and Tim Budisantoso kun is first author of the paper4Online version of Neuron of the month 28 days.。

Kainate receptors of the glutamate receptor、There was particularly high in specific synapses of the hippocampus, an important brain region in memory and learning、The transmission rate that is slow not to other receptors、And the essential role in the integration of hippocampal neural network activity。However、Whether incorporated only to certain synaptic kainate receptors what mechanism、The mechanism was not well understood。In this paper, the、By neurons secrete proteins called the C1ql2 and C1ql3、I found that coming to collect the kainate receptors directly。Also、In the hippocampus of mice lacking the C1ql2 and C1ql3、Kainate receptors is not incorporated into the synapse、Be less likely to occur epileptic seizures was found be given a stimulus to induce epileptic artificially。

C1ql2、C1ql3 is also present in various brain regions、Are considered each by controlling the built-in and function of kainate receptor synaptic neural make up the appropriate neural network activity。The results of this research、It is expected to be of use in the therapy method development and cause elucidation of epilepsy and autism。

This paper、As this month's attention paper of Neuron magazinePreview “Synaptic Menage a Trois”Was introduced as (ThreesomesPlease check out our own meaning of。）

Koda, Associate Prof. promotion as St. Marianna University School of Medicine Department of Physiology professor from April 1。1996St. Jude (but was back in the temporary Tokyo University psychiatry in the middle) Children's Research yuzu Saki Institute at the hospital since joined as the first post-doc at the time of the birth is the beginnings of the oldest founding life member in year。I wish more and more of your success future。

4It belated celebration meeting a month 15 days (farewell party) at the Art Complex。As Koda teacher himself Violin player、Miura (Violin)、Nozawa Jun (Viola)、Great string quartet by Takeo's (Cello) have been made。Photos here→

Papers about the synapse control by the Notch of Takeo Assistant Professor (Adjunct)Scientific Reports.。It is what the work in Tomita Research finally settled。Congratulations!。

Dr. Christophe Mulle (CNRS, University of Bordeaux, Bordeaux, France) gave a talk entitled “Synaptic dysfunction in a memory circuit in models of Alzheimer’s disease” at the 108th Brain Club on March 28th.

This year two teams from yuzu Saki Institute as the first attemptTamagawa Riverside EkidenI participated in。Cbln1 a team and C1qL1 team。Cheers for good work Did!

3month15It gave a farewell Mukaekai of 2016 on the day。This time, the welcome of Nozawa-kun of graduate students (MSc) and conference-kun (PhD)、It is Narumi-kun of the pick-up that who have supported for many years laboratory。Narumi-kun of the favorite food (such as fried) was conducted in the lab a wide variety。Photos here。

ToshibaOnline magazine "has Wereki"Interview article for the general public of Yuzusaki was published in the。

Prof. Ryohei Yasuda (Scientific Director, Max Planck Florida Institute for Neuroscience) gave a talk entitled “Illuminating signal transduction in single dendritic spines” at the 107th Brain Club.

A review of Kakegawa, Mazda Yuzusaki "Complement C1q family molecules and the formation and maintenance of synapses" isAnnual Review神経2016.。

Prof. Takao Hensch (Children’s Hosp, Harvard Univ) gave a talk entitled “Balancing plasticity/stability across brain development” at the 106th Brain Club.

Kakegawa lecturer was awarded the Koyo Sakaguchi Memorial Keio University Medical Science Fund Medical Research Award。1 It was honored at the annual School of Medicine, New Year celebration ceremony held to 5 days a month。Congratulations!

We will soon start a new series of Neuroscience Book Reading Club.
We have picked up "Principles of Neurobiology" this time. This book was written by a single author,. Liqun Luo is all text of the written neurobiology alone。If you want to study neurobiology、or English、and who is interested in reading circle、Anyone、By all means we are welcome to join。

A meeting will be held on every Saturday morning 10:00Although we plan to - about 1 hour、Please contact us for more information。Dates can be also be changed by discussion of participants。Tour is also a big welcome。