Even in everyday life、Even in nature world、When making something new、Oftentimes, you must break the old one before that。When the morphology of nerve cells changes in our brain according to the developmental stage and memory / learning、Cooperately、It is always accompanied by the destruction of nerve cells and the extracellular matrix around them.。As one of the mechanisms responsible for such a scrap and build phenomenon、The secretion of lysosomes from nerve cells is raising attention。Although lysosomes are usually known as the final digestion site for aging intracellular products,、,、We have found that, In response to hyperactivity, it releases the synapse-forming molecule Cbln1 with the lysosome enzyme, which is the content of the lysosome (Neuron 2019).。In this review paper、we overviewed lysosome secretion in the nervous system。Dr. Ibata, who has transferred to St. Marianna University, is the first author.。

04/17/2021 11:05 PM | What's New