Assistant Professor Iijima's paperJournal of NeuroscienceIt became Accept to。"Cbln1 is expressed suppressed by neural activity - homeostatic control in the development stage and mature stage" is the title of。

We、We previously reported that the new secreted factor Cbln1 is essential to maintain and synapse formation between cerebellar granule cells and Purkinje cells。In this paper、When neural activity in granule cells continuously increased to Cbln1 expression is decreased、As a result, we found that the synapse is out。With such a mechanism、Or maintaining the homeostasis prevent over-excitement、Possibility of motor learning related to that and go synaptic modification is suggested。

03/26/2009 1:02 AM | What's New