Thesis of Matsuda Assistant Professor is now Accept the Neuron。Congrats。

AMPA receptor is responsible for the fast neurotransmitter in our brain、We have to control the memory and learning process。AMPA receptors are usually transported to the postsynaptic (dendrites)、Do not go to the presynaptic (axons)。The mechanism of this "polar transport" It was long a mystery、We、AP-4 of the adapter protein that controls the vesicular transport membrane proteins、Was the first time revealed that responsible for this polarity transport。further、Since AMPA receptors that are erroneously transported to the axon is decomposed captured by autophagosomes transchromosomic internally axon、AP-4 is to be involved in autophagy activity has been suggested。

This work is the result of joint research with Hokkaido University Miura, Watanabe teacher。

02/08/2008 12:55 AM | What's New