Graduate students of Nishiyama Mr. of paper is now Accept the Autophagy magazine。Congrats。

The relationship between the nerve cell death and autophagy has been attracting attention。For example,、In lurcher mutant mice、When the Delta 2 receptor is constantly activated、Neurodegenerative be seen along with the enhancement of autophagy in Purkinje cells。This molecular mechanism has been conducting research in our laboratory。

In this research、The Atg5 gene is essential for autophagy pathway has been created and studied the Purkinje cell-specific defects are not mice。Prior to denaturation of the Purkinje cells Interestingly、Swelling of the axons is observed、Image intracellular membrane structure is accumulation was observed in tumor most。It is considered an important finding in considering the origin and role of the auto phagocytosis transchromosomic in nerve cells。(Is a joint research with Ken Watanabe Medicine and Dentistry of Ken Mizushima Hokkaido University。）

09/05/2007 12:53 AM | What's New