Translation

Welcome to Yuzaki Lab
  • Yuzuzaki Laboratory is a research center for human biology - Microbiota - Quantum Computational Research (Keio University)WPI-Bio2Q) has been moved to
  • Focusing on synaptic formation mechanisms in the central nervous system, peripheral nervous system, autonomic nervous system, and enteric nervous system、We aim to clarify the linkage between the nervous system and multiple organs, and the pathology caused by its failure, and to develop treatment methods.
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We await the participation of motivated indivisuals。We will vigorously nurture young researchers who will lead the future of basic science.。
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The paper on cerebellar motor learning and LTD came out in Neuron magazine

Activity-dependent endocytosis of AMPA receptors at postsynaptic sites、which underlies long-term depression (LTD), is thought to mediate certain forms of learning and memory in vivo。However、whether LTD at synaptic levels is causally related to learning and memory at system levels has remained unclear。In thisNeuron paper、using a new optogenetic tool, termed PhotonSABER, which could acutely and reversibly inhibit LTD in a light-dependent manner、we show that LTD at parallel fiber-Purkinje cell synapses、is essential for eye movement-based motor learning in vivo。Dr. Kakegawa, Associate Professor at Keio University、and Dr. Matsuda, Associate Professor at the University of Electro-Communications、performed all experiments with great helps from Dr. Kato, Associate Professor (Tokai Univ.), Dr. Fukasawa, Professor (Fukui Univ) and Dr. Kohda, Professor (St. Mali University School of Medicine)。

TheVideo Abstract has been published in Neuron.。YouTube is here.→。

08/17/2018 12:53 PM | What's New

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