Cbln1 inhibits formation and function of inhibitory synapses between interneurons and Purkinje cells
One of the formation and function of the excitatory synaptic and inhibitory synaptic input to the nerve cells is believed to have been controlled in conjunction with each other, but we do not know well the entity。Cerebellar parallel fibers and secretion in this paper、Is Cbln1 to strongly promote the formation of a functional excitatory synapses between Purkinje cell - parallel fibers、It has revealed that to suppress the formation and function of inhibitory synapses intervening neural over Purkinje intercellular。This studyEuropean Journal of Neuroscience.。Ishida's graduate student OB's work centered on the (currently studying in the United States)。
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